Vraylar Interactions: Alcohol, Medications, and Others
Vraylar (cariprazine) is a prescription drug that helps deal with sure psychological well being circumstances. It can
work together with alcohol, different medicines, and a few dietary supplements. For instance, Vraylar can work together with
bupropion (Wellbutrin, Aplenzin, others) and aripiprazole (Abilify, others).
Vraylar is utilized in adults to deal with:
manic, depressive, or combined episodes of bipolar I dysfunction
schizophrenia
melancholy (when taken with an antidepressant)
An interplay can happen as a result of one substance causes one other substance to have a distinct impact than anticipated. Interactions also can happen when you have sure well being circumstances.
Keep studying to find out about Vraylar’s attainable interactions. And for extra details about Vraylar, together with particulars about its makes use of, see this text.
When ought to I keep away from Vraylar?
When ought to I keep away from Vraylar?
Certain well being circumstances or different elements may elevate your danger of hurt in the event you take Vraylar. In such circumstances, your physician could not prescribe the drug for you. These are referred to as contraindications. Vraylar’s contraindication is described under.
If you’ve had an allergic response. If you’ve had an allergic response to Vraylar or any of its substances, your physician doubtless received’t prescribe Vraylar. This is as a result of taking the drug may trigger one other allergic response. You can ask your physician about different therapies that could be higher choices for you.
* Are you on the lookout for Info & Tips? You can discover it under *
Does Vraylar work together with alcohol?
Does Vraylar work together with alcohol?
It is probably not secure to drink alcohol throughout Vraylar remedy.
Consuming alcohol with Vraylar could elevate your danger of sure negative effects with the drug. These embody dizziness, sleepiness, and slowed actions. (For extra details about Vraylar’s negative effects, see this text.)
Drinking alcohol also can worsen sure signs of psychological well being circumstances, equivalent to bipolar melancholy.
If you drink alcohol, discuss together with your physician about how a lot (if any) could also be secure to eat together with your situation and remedy plan.
Does Vraylar work together with different medication?
Does Vraylar work together with different medication?
Before you begin taking Vraylar, inform your physician and pharmacist about any prescription, over-the-counter, or different medication you are taking. Sharing this data with them could assist forestall attainable interactions. (To be taught whether or not Vraylar interacts with dietary supplements, herbs, and nutritional vitamins, see the “Are there other interactions with Vraylar?” part under.)
If you could have questions on drug interactions that will have an effect on you, discuss together with your physician or pharmacist.
The desk under lists medication that will work together with Vraylar. Keep in thoughts that this desk doesn’t embody all medication that will work together with Vraylar. For extra details about a few of these interactions, see the “Drug interactions explained” part under.
Drug group or drug titleDrug examplesWhat can occur
different antipsychotic medication*• aripiprazole (Abilify, Abilify Maintena, others)
• quetiapine (Seroquel, Seroquel XR)
• ziprasidone (Geodon)
• lurasidone (Latuda)
• iloperidone (Fanapt)can improve the danger of negative effects from Vraylar† and the opposite antipsychotic medication
benzodiazepines• alprazolam (Xanax, Xanax XR)
• diazepam (Valium)
• lorazepam (Ativan, Loreev XR)can improve the danger of negative effects from Vraylar
tricyclic antidepressants (TCAs)• amitriptyline
• imipramine (Tofranil)
• clomipramine (Anafranil)can improve the danger of negative effects from Vraylar and TCAs
monoamine oxidase inhibitors (MAOIs)• selegiline (Emsam, Zelepar)
• phenelzine (Nardil)
• isocarboxazid (Marplan)can improve the danger of negative effects from Vraylar and MAOIs
blood stress medication• atenolol (Tenormin)
• clonidine (Catapres-TTS, Kapvay, Nexiclon XR)
• nifedipine (Procardia, Procardia XL)may decrease your blood stress an excessive amount of
sure seizure medication• oxcarbazepine (Oxtellar XR, Trileptal)
• carbamazepine (Carbatrol, Tegretol, others)
• phenytoin (Dilantin, Phenytek)could make Vraylar much less efficient
sure antibiotics• rifampin (Rifadin, Rimactane)
• ciprofloxacin (Cipro)
• clarithromycincan improve the danger of negative effects from Vraylar or make Vraylar much less efficient
sure antifungals• voriconazole (Vfend)
• ketoconazole
• itraconazole (Sporanox, Tolsura)can improve the danger of negative effects from Vraylar
diphenhydramine (Benadryl)—can improve the danger of negative effects from Vraylar
bupropion (Wellbutrin SR, Wellbutrin XL, Aplenzin, others)—can improve the danger of negative effects from Vraylar and bupropion
* Vraylar is an atypical antipsychotic, which is a more moderen group of antipsychotic medication.
† To be taught extra about Vraylar’s negative effects, see this text.
Drug interactions defined
Drug interactions defined
Learn extra about sure drug interactions that may happen with Vraylar.
Interaction with bupropion
Vraylar can work together with bupropion (Wellbutrin SR, Wellbutrin XL, Aplenzin, others). Bupropion is prescribed to deal with sure psychological well being circumstances. Examples embody melancholy and seasonal affective dysfunction.
Taking Vraylar with bupropion can elevate the danger of negative effects from each medication.
What may occur
Both Vraylar and bupropion could trigger seizures. Taking these medicines collectively can improve your danger of seizures much more.
What you are able to do
Before beginning Vraylar remedy, let your physician know in the event you’re taking bupropion. They can let you know whether or not it’s secure to take these medicines collectively.
If you are taking Vraylar with bupropion, let your physician know instantly when you have a seizure.
In some circumstances, your physician could prescribe a decrease dosage of bupropion to assist cut back your danger of seizures. If you could have questions on Vraylar and bupropion, discuss together with your physician or pharmacist.
Interaction with diphenhydramine
Vraylar can work together with diphenhydramine (Benadryl, ZzzQuil, others). Diphenhydramine is an antihistamine that’s used to ease signs of colds and allergy symptoms.
Taking Vraylar with diphenhydramine may elevate your danger of negative effects from Vraylar.
What may occur
Taking Vraylar with diphenhydramine could elevate your danger of sure negative effects from Vraylar. These embody sleepiness, dizziness, and slowed actions. For extra details about Vraylar’s negative effects, see this text.
What you are able to do
If you’re all for taking Vraylar with diphenhydramine, discuss together with your physician or pharmacist first. They can advise you on whether or not these medicines are secure to take collectively. If wanted, they’ll suggest a distinct remedy to ease signs of colds and allergy symptoms.
Interaction with different antipsychotic medication
Vraylar is an antipsychotic drug, and it will possibly work together with different medication on this group.
Antipsychotics are used to deal with schizophrenia and different psychological well being circumstances. Vraylar is an atypical antipsychotic, which is a more moderen group of antipsychotic medication.
Taking Vraylar with different antipsychotic medication can elevate your danger of negative effects from Vraylar and different antipsychotics.
Examples of antipsychotic medication embody:
aripiprazole (Abilify, Abilify Maintena, others)
quetiapine (Seroquel, Seroquel XR)
ziprasidone (Geodon)
lurasidone (Latuda)
iloperidone (Fanapt)
What may occur
Vraylar and different antipsychotic medication could trigger comparable negative effects. A number of examples embody dizziness, sleepiness, and seizures. Taking these medication collectively can additional improve your danger of those negative effects. (To be taught extra about Vraylar’s negative effects, see this text.)
What you are able to do
Before taking Vraylar, inform your physician about every other antipsychotic medication you are taking. They’ll decide whether or not you may safely take Vraylar with these medication.
If you could have questions on taking Vraylar with different antipsychotics, discuss together with your physician or pharmacist.
Are there different interactions with Vraylar?
Are there different interactions with Vraylar?
Vraylar could produce other interactions. They may happen with dietary supplements, meals, vaccines, and even lab checks. See under for particulars. Note that the data under doesn’t embody all different attainable interactions with Vraylar.
Does Vraylar work together with dietary supplements?
Before you begin taking Vraylar, discuss together with your physician and pharmacist about any dietary supplements, herbs, and nutritional vitamins you are taking. Sharing this data with them could assist you to keep away from attainable interactions.
If you could have questions on interactions that will have an effect on you, discuss together with your physician or pharmacist.
Vraylar interactions with herbs
Vraylar could work together with a complement known as St. John’s wort. (This complement could also be used to assist ease signs of melancholy and different well being circumstances.)
Taking Vraylar with St. John’s wort could make Vraylar much less efficient.
Before beginning Vraylar, inform your physician in the event you take St. John’s wort. They’ll sometimes suggest that you don’t take Vraylar with this complement. Your physician could recommend you cease taking St. John’s wort, or they might prescribe a drug aside from Vraylar.
Vraylar and nutritional vitamins
There are at the moment no stories of Vraylar interacting with nutritional vitamins. But this doesn’t imply that vitamin interactions received’t be acknowledged sooner or later.
For this cause, it’s nonetheless essential to test together with your physician or pharmacist earlier than taking any of those merchandise throughout remedy with Vraylar.
Does Vraylar work together with meals?
There are at the moment no stories of Vraylar interacting with meals. If you could have questions on consuming sure meals throughout your remedy with Vraylar, discuss together with your physician.
Does Vraylar work together with vaccines?
There are at the moment no stories of Vraylar interacting with vaccines. If you could have questions on getting sure vaccines whereas taking Vraylar, discuss together with your physician.
Does Vraylar work together with lab checks?
There are at the moment no stories of Vraylar interacting with lab checks. If you could have questions on having sure lab checks whereas taking Vraylar, discuss together with your physician.
Does Vraylar Interact with hashish or CBD?
Cannabis (generally known as marijuana) and hashish merchandise, equivalent to cannabidiol (CBD), have been particularly reported to work together with Vraylar.
Using hashish or hashish merchandise with Vraylar could elevate your danger of sure negative effects with Vraylar. These embody dizziness, sleepiness, and slowed actions. (For extra details about Vraylar’s negative effects, see this text.)
Before you begin remedy with Vraylar, inform your physician and pharmacist in the event you use hashish. By sharing this data with them, it’s possible you’ll assist forestall attainable interactions.
Note: Cannabis is prohibited at a federal degree however is authorized in lots of states to various levels.
Does my well being historical past have an effect on whether or not I ought to take Vraylar?
Does my well being historical past have an effect on whether or not I ought to take Vraylar?
Certain medical circumstances or different well being elements could elevate the danger of interactions with Vraylar. Before taking Vraylar, discuss together with your physician about your well being historical past. They’ll decide whether or not Vraylar is best for you.
Health circumstances or different elements which may work together with Vraylar embody:
Being age 24 years or youthful. Vraylar could improve the danger of suicidal ideas and behaviors in kids and younger adults (ages 18–24 years). In reality, the drug has a boxed warning about this danger. For extra data, see the “Boxed warnings” part at the start of this text.
Being age 65 years or older and having dementia-related psychosis. Vraylar could improve the danger of loss of life in older adults with psychosis associated to dementia. This danger impacts folks ages 65 years and older. In reality, the drug has a boxed warning about this danger. For extra data, see the “Boxed warnings” part at the start of this text.
Having coronary heart issues or having had a stroke. Before beginning Vraylar remedy, inform your physician when you have a coronary heart downside or in the event you’ve ever had a stroke. Examples of coronary heart issues embody coronary heart assault and coronary heart failure. These circumstances may elevate your danger of getting orthostatic hypotension (a drop in blood stress when standing or sitting up) from Vraylar.
Your physician can decide whether or not it’s secure so that you can take Vraylar.
Severe liver or kidney issues. It isn’t recognized whether or not Vraylar is secure for folks with extreme liver or kidney issues. Examples embody liver failure and kidney failure.
If you could have a extreme liver or kidney downside, discuss together with your physician earlier than beginning Vraylar remedy. They can suggest the suitable remedy choice for you.
Diabetes. Vraylar could trigger excessive blood sugar. If you could have diabetes, taking Vraylar may worsen your situation. Your physician could have you ever test your blood sugar extra typically than regular when you’re taking Vraylar.
High ldl cholesterol or triglyceride ranges. Vraylar could trigger excessive ldl cholesterol or triglyceride ranges as a facet impact. If you have already got excessive ldl cholesterol or triglyceride ranges, this drug may worsen your situation. Your physician could test your ranges extra typically than regular throughout your Vraylar remedy.
Seizures. Vraylar could trigger seizures. Before taking the drug, inform your physician when you have seizures or have had them previously. They can decide whether or not it’s secure so that you can take Vraylar.
Low white blood cell ranges. Vraylar could decrease the degrees of white blood cells in your physique. This facet impact may improve your danger of an infection.
Before beginning Vraylar remedy, your physician could test your white blood cell ranges. If your ranges are low, they might recommend a distinct remedy choice on your situation.
Pregnancy. It isn’t recognized whether or not Vraylar is secure to take throughout being pregnant. If you’re pregnant or planning a being pregnant, discuss together with your physician earlier than beginning Vraylar remedy.
If you are taking Vraylar whereas pregnant, take into account becoming a member of the National Pregnancy Registry for Atypical Antipsychotics. This registry collects details about the security of Vraylar and comparable medicines throughout being pregnant. To be taught extra, go to the registry’s web site or name 866-961-2388. You also can ask your physician for extra data.
Breastfeeding. It isn’t recognized whether or not Vraylar is secure to take whereas breastfeeding. It’s not recognized if the drug passes into breast milk or causes negative effects in a baby who’s breastfed. If you’re breastfeeding or planning to take action, discuss together with your physician earlier than beginning Vraylar remedy.
Allergic response. If you’ve had an allergic response to Vraylar or any of its substances, your physician will doubtless not prescribe Vraylar. This is as a result of taking the drug may trigger one other allergic response. You can ask your physician about different therapies that could be higher selections for you.
Common questions on Vraylar and interactions
Common questions on Vraylar and interactions
Find solutions under to some continuously requested questions on Vraylar and attainable interactions.
Can I take Vraylar and Lamictal collectively?
Yes, in case your physician tells you it’s secure. These medicines aren’t recognized to work together with one another. Your physician could prescribe Vraylar with lamotrigine (Lamictal) to deal with bipolar I dysfunction.
Vraylar is used to deal with sure temper episodes with bipolar I dysfunction. These embody the short-term remedy of manicor combined episodes or the long-term remedy of depressive episodes. Lamictal can be utilized to assist improve the time between temper episodes associated to bipolar I dysfunction.
Your physician will decide whether or not you must take Vraylar with Lamictal or one other temper stabilizer. If wanted, they’ll suggest the drug mixture that’s proper for treating your situation.
If you could have questions on Vraylar and Lamictal, discuss together with your physician or pharmacist.
Is it secure to take Vraylar and Lexapro collectively?
Yes, it needs to be secure to take Vraylar with Lexapro (escitalopram). These medication aren’t recognized to work together with one another.
Lexapro is a sort of drug known as an antidepressant. If you are taking Vraylar for melancholy, your physician could prescribe it together with an antidepressant equivalent to Lexapro.
Keep in thoughts that Vraylar could work together with sure different antidepressants. These embody:
tricyclic antidepressants (TCAs), equivalent to amitriptyline
monoamine oxidase inhibitors (MAOIs), equivalent to phenelzine (Nardil)
bupropion* (Wellbutrin SR, Wellbutrin XL)
If you could have different questions on taking Vraylar with Lexapro or one other antidepressant, discuss together with your physician or pharmacist.
* To find out about Vraylar’s interplay with bupropion, see the “Drug interactions explained” part above.
Will my physician prescribe Vraylar and Effexor XR collectively?
It’s attainable.
Venlafaxine (Effexor XR) is an antidepressant. Your physician could prescribe Vraylar with an antidepressant to deal with melancholy.
Your physician could suggest Effexor XR for this use. Vraylar and Effexor XR aren’t recognized to work together with one another.
It’s essential to notice that Vraylar can work together with antidepressants aside from Effexor XR. These embody:
TCAs, equivalent to amitriptyline
MAOIs, equivalent to phenelzine (Nardil)
bupropion (Wellbutrin SR, Wellbutrin XL)
For particulars about Vraylar’s interplay with bupropion, see “Drug interactions explained” above.
To be taught extra about taking Vraylar with Effexor XR or one other antidepressant, discuss together with your physician or pharmacist.
How can I forestall interactions?
How can I forestall interactions?
Taking sure steps might help you keep away from interactions with Vraylar. Before beginning remedy, discuss together with your physician and pharmacist. Things to debate with them embody:
Whether you drink alcohol or use hashish.
Other medicines you are taking, in addition to any nutritional vitamins, dietary supplements, and herbs. Your physician or pharmacist might help you fill out a drugs record.
What to do in the event you begin taking a brand new drug throughout your Vraylar remedy.
It’s additionally essential to grasp Vraylar’s label and different paperwork that will include the drug. Colored stickers that describe interactions could also be on the label. And the paperwork (generally known as the affected person package deal insert or medicine information) could produce other particulars about interactions. (If you didn’t get paperwork with Vraylar, ask your pharmacist to print a replica for you.)
If you could have bother studying or understanding this data, your physician or pharmacist might help.
Taking Vraylar precisely as prescribed also can assist forestall interactions.
